EEG Based Stratified Psychiatry in ADHD and Depression: QEEG Validation studies of Brainmarker-I and other biomarkers
Martijn Arns, PhD, BCN
1-day workshop
Date: to be confirmed
Workshop Title
EEG Based Stratified Psychiatry in ADHD and Depression: QEEG Validation Studies of Brainmarker-I and other Biomarkers
Workshop Description
Deciding between different evidence-based treatment options in mental health care still relies on trial-and-error following the stepped-care approach (escalating from least intensive to more intensive treatments after treatment failures). Much recent research is focused on biomarkers and precision psychiatry, however here I will present that stratified psychiatry could be a more practical and realistic alternative capable of leveraging elements from stepped-care to develop a much more suitable and realistic stratified matched-care approach to serve our patients suffering from mental health disorders. In this presentation the development, validation and out-of-sample validation of Brainmarker-I (an alpha frequency-based biomarker) for treatment stratification in ADHD (neurofeedback vs. methylphenidate) and Depression (psychotherapy, sertraline, venlafaxine, TMS-protocols, ECT and Ketamine) treatments will be presented. Validation and development was performed on the TDBRAIN+ EEG dataset comprising N>4000, and blinded-out-of-sample validations for stratification performance in external datasets. In addition, new insights for other Brainmarkers will be presented including EEG-network analyses (fICA) and the beta-spindle inspired Brainmarker-III.
Learning Objectives
1) Learn to understand the concept of stratified psychiatry and how it is different from one-size-fits all and precision psychiatry.
2) Understand the importance of replication, validation and clinical relevance.
3) Learn how EEG is not a diagnostic but prognostic tool in psychiatry.
4) Learn how Brainmarker-I was developed and what it measures.
About Martijn Arns, PhD, BCN
Research Director @Brainclinics Foundation
Visiting Scholar @Stanford Brain Stimulation Lab, Stanford University
Associate Professor @Maastricht University
Dr. Martijn Arns is a biological psychologist, applied neuroscientist, and entrepreneur with over two decades of experience at the intersection of neuroscience, neurofeedback, psychiatry, and technology. He is the founder of the Brainclinics Foundation, dedicated to translating neuroscience research into clinically actionable treatments. Currently, he serves as Associate Professor at Maastricht University and Visiting Scholar at Stanford University. With over 170 publications, multiple patents, and several spin-offs to his name, Dr. Arns is a leading voice in neuromodulation, brain stimulation, and precision psychiatry.
